—Can you come and play football with me? —. I have a lot of homework to do.A. Of courseB.

问题补充：

—Can you come and play football with me?

—. I have a lot of homework to do.

A. Of course

B. I’d like to

C. I’m afraid not

D. It’s a pleasure

答案：

A. Of course

B. I’d like to

(答案→)C. I’m afraid not

D. It’s a pleasure

解析：根据语境可知此句的含义是你能不能和我一起踢足球，表示的是一种请求或邀请表示肯定答语的是of course或certainly；表示否定回答的时候常用sorry或I’m afraid not等形式，再加上拒绝的理由，因题干中出现了语句I have a lot of homework to do.说明拒绝了对方的邀请，故选C。