手性拆分,Chiral separation
1)Chiral separation手性拆分
1.Study on the chiral separation of triadtanefon enantiomers;三唑酮对映体的手性拆分研究
2.Enantiomeric separation of zopiclone by chiral separation;手性拆分柱法用于佐匹克隆对映体的拆分
3.Chiral separation of terbutaline by reversed-phase high performance liquid chromatography;反相高效液相色谱手性拆分特布他林
英文短句/例句
1.Study of Chiral Separation of Tryptophan Enantiomers and Process Simulation;色氨酸对映体的手性拆分及过程模拟
2.Chiral Separation of N-Fmoc Amino Acids by Capillary Electrophoresis;毛细管电泳手性拆分N-Fmoc保护氨基酸
3.The Synthesis and Chiral Resolution of Azelnidipine;阿折地平的合成及手性拆分方法研究
4.Chiral Resolution by Capillary Electrophoresis and its Future Trends;毛细管电泳手性拆分研究及应用进展
5.Chiral Resolution of Tetrahydrofuran-2-formic Acid四氢呋喃-2-甲酸的手性拆分研究
6.Preparation of covalently bonded cellulose-derived chiral stationary phase and enantioseparation键合纤维素手性固定相的合成及手性拆分
7.Study on the Separation and Toxicity of Enantiomers of Beta-Cypermethrin;高效氯氰菊酯的手性拆分及其对映体毒性研究
8.Control factors of enantioselectivity in lipase-catalyzed chiral resolutions脂肪酶促手性拆分中立体选择性的调控因素
9.Chiral Stationary Phases Based on Optically Active Polymers: Synthesis and Their Chiral Resolution Performance;光学活性聚合物基手性固定相的制备及其手性拆分性能
10.Enantiomeric Separation of Dethmor by High Performance Capillary Electrophoresis杀鼠灵对映体的高效毛细管电泳手性拆分
11.Capillary Electrophoresis Enantioseparation with Maltose as Chiral Selector;麦芽糖作选择剂的毛细管电泳手性拆分
12.The Synthesis and Chiral Resolution of DL-phenylalanine and Its Derivatives;外消旋苯丙氨酸及其衍生物的合成与手性拆分
13.Drug Enantiomer of Separation by High Performance Liquid Chromatography Chiral Stationary Phase;依托度酸及其中间体的高效液相色谱手性拆分
14.Catalystic Additions of Styrene Oxide and Chiral Separation of the Adducts;环氧苯乙烷的催化加成及其产物的手性拆分
15.The Study on Chiral Separation of Fenvalerate and Their Stress Effects on Platymonas Subcordiformis;氰戊菊酯手性拆分及其对扁藻胁迫作用的研究
16.Study on Chiral Resolution of Enantiomers of β-adrenergic Drugs;β-肾上腺素类药物对映体的手性拆分研究
17.Chiral Drug Separation by Binary Cyclodextrin Systems and the Chiral Drug Separation Database;二元环糊精体系手性药物拆分及手性药物拆分数据库
18.Resolution of Enantiomeric Drugs by Supercritical Fluid Extraction;超临界流体萃取拆分手性药物的研究
相关短句/例句
chiral resolution手性拆分
1.Advance in chemical synthesis andchiral resolution of l-menthol;l-薄荷醇的合成及手性拆分研究进展
2.Study on thechiral resolution of fluroxypyr-meptyl;氟草烟异辛酯对映体的手性拆分
3.Development and application of membranes forchiral resolutions;手性拆分膜的研究与应用新进展
3)enantioseparation手性拆分
1.Application of Sulfated-cyclodextrin in Capillary Electrophoretic Enantioseparation;硫酸化环糊精在毛细管电泳手性拆分中的应用
2.Besides, solid membrane separation has become one of most important methods for theenantioseparation.近年来,单一对映体手性药物的制备成为药物开发的热点之一,手性拆分作为获得单一对映体的有效途径之一已被广泛应用于外消旋药物的拆分和"消旋药物的转变"过程中。
3.The influence of the mobile phase composition on the enantioselectivity was discussed, and the effect of structural variation of the solutes on theirenantioseparation was also investigated and compared.正相条件下 ,在自制的涂敷型纤维素 -三 ( 3 ,5 二甲基苯基氨基甲酸酯 )手性固定相上 ,首次直接拆分了几种新的外消旋过渡金属簇合物 ,考察了流动相中极性添加剂对手性拆分的影响 。
4)enantiomeric separation手性拆分
1.Theenantiomeric separation of six basic and two acidic chiral drugs was accomplished.考察了背景电解质pH及磺丁基-β-环糊精浓度对手性拆分的影响,应用磺丁基-β-环糊精拆分八对碱性和酸性的药物对映体。
2.Theenantiomeric separation of four acidic drugs and one neutral drug on human serum albumin(HSA) chiral stationary phase was described.这5种药物与人血清白蛋白结合的亲和力高,难于实现快速分离,作者提出在流动相中加入短链脂肪酸-正己酸,可快速手性拆分非诺洛芬、萘普生和布洛芬。
3.Objective:To synthesize β-CD carboxymethyl ether and use it as chiral additive of capillary zone electrophoresis forenantiomeric separation of terbutaline.目的:合成β环糊精羧甲醚并以其作为毛细管电泳手性添加剂对特布他林进行手性拆分研究。
5)Enantiomer separation手性拆分
6)Resolving agent手性拆分剂
延伸阅读
拆分分子式:CAS号:性质:用适当的方法将外消旋体里包含的两种对映体彼此分开,得到纯净的d体和l体的过程。方法如下。(1)晶体的机械分离法,根据两种对映体的晶形不同,在显微镜下慢慢用镊子挑选而达到分离。此法不能拆分液态化合物,而且比较麻烦,已被淘汰。(2)生化法,用微生物或酶来破坏外消旋体中的一种对映异构体而达到提纯的目的。缺点是操作过程要引入培养微生物或酶的原料纯化困难;拆分过程中至少要浪费一半的原料。(3)不对称反应析解法,让外消旋体与一种有旋光性拆分剂作用,生成非对映异构体,然后根据生成物物理性质的不同而加以分离。这是目前最常用的拆分法。(4)播种结晶法,根据对映体在溶液中具有不同的晶间力而进行拆分。(5)吸附法,根据对映异构体吸附能力不同而加以分离。