比较分子相似性指数法,comparative molecular similarity indices analysis
CoMSIA比较分子相似性指数分析法
1.For theCoMSIA study,the influence of the combination of different field types was evaluated and the best combination was considered to be of steric,electrostatic,hydrophobic and H-bonding acce.采用比较分子力场分析法(CoMFA)和比较分子相似性指数分析法(CoMSIA),系统研究了49个新型四氢萘类化合物抗真菌活性的三维定量构效关系。
2.Using comparative molecular field analysis (CoMFA) and comparative molecular similarity in-dices analysis (CoMSIA), three dimensional structure-activity relationship (3D-QSAR) has been studied on a series of novel triazole antifungal compounds.采用比较分子力场分析法(CoMFA)和比较分子相似性指数分析法(CoMSIA),系统研究了40个新型三唑类化合物抗真菌活性的三维定量构效关系。
3.Using comparative molecular field analysis(CoMFA) and comparative similarity indices analysis(CoMSIA),three dimensional structure-activity relationship(3D-QSAR) was studied on inhibitors of CDK4.采用比较分子场分析法(comparative molecular field analysis,CoMFA)和比较分子相似性指数分析法(comparative similarity indices analysis,CoMSIA),系统研究了57个CDK4酶抑制剂的三维定量结构-活性关系。
3)CoMFA/CoMSIA比较分子场/比较分子相似性指数
4)CoMSIA比较分子相似性指数分析
1.The three-dimensional quantitative structure-activity relationships of N, N-dimethyl-2-bromo-2-phenylethylamine were systematically studied by using comparative molecular field analysis (CoMFA) and comparative molecular similarity indices analysis (CoMSIA).用比较分子力场分析(CoMFA)法和比较分子相似性指数分析(CoMSIA)法,建立N,N-二甲基-2-溴苯乙胺类化合物的3D-QSAR模型。
2.On the basis of published papers, comparative molecular field analysis (CoMFA) and comparative molecular similiarity indices analysis (CoMSIA) were used to gain insight into the three dimensional quantitative structure activity relationships (3D-QSAR) of benzoxazinone derivatives.苯并噁嗪酮衍生物是近年来发现的一类抗血小板聚集化合物,在前人研究的基础上利用比较分子场分析(CoMFA)和比较分子相似性指数分析(CoMSIA)对23个苯并噁嗪酮衍生物进行了三维定量构效关系(3D-QSAR)研究。
3.The molecular docking followed by comparative molecular field analysis (CoMFA) and com- parative molecular similarity index analysis (CoMSIA) was employed to the three-dimensional quantitative structure-activity relationship (3D-QSAR) studies of estrogen receptor-β of 33 quinoline derivatives.对33个喹啉衍生物的雌激素β受体活性进行了分子对接以及比较分子力场分析(CoMFA)和比较分子相似性指数分析(CoMSIA)。
5)Comparative molecular similarity indices analysis (CoMSIA)比较分子相似性指数分析(CoMSIA)
6)comparative molecular similarity indices analysis(CoMSIA)比较分子相似性分析
延伸阅读
比较比较两种事物之间的对比，诸如大小、高低、长短、前后、上下、左右、精神、营养、病情等都可作比较。
